The ISL22343 integrates four digitally controlled potentiometers (DCP), control logic and non-volatile memory on a monolithic CMOS integrated circuit. The digitally controlled potentiometer is implemented with a combination of resistor elements and CMOS switches. The position of the wipers are controlled by the user through the I2C bus interface. The potentiometer has an associated volatile Wiper Register (WRi) and a non-volatile Initial Value Register (IVRi) that can be directly written to and read by the user. The contents of the WRi control the position of the corresponding wiper. At power up the device recalls the contents of the DCP's IVRi to the correspondent WRi. The ISL22343 also has 11 general purpose non-volatile registers that can be used as storage of lookup table for multiple wiper position or any other valuable information. The ISL22343 features a dual supply, that is beneficial for applications requiring a bipolar range for DCP terminals between V- and VCC. Each DCP can be used as three-terminal potentiometers or as two-terminal variable resistors in a wide variety of applications including control, parameter adjustments, and signal processing.